VIỆN VỆ SINH DỊCH TỄ TRUNG ƯƠNG TUYỂN DỤNG

The Eliminate Dengue Program is a large multi-institution research program led by Professor Scott O’Neill, Director of Institute of Vector-borne Disease (IVBD)at Monash University. It is developing a new approach lớn control mosquito-borne diseases such as dengue (www.eliminatedengue.com). The work is funded primarily through the Grand Challenges in Global Health initiative of the Bill & Melinda Gates Foundation. In Vietnam the National Institute for Hygiene & Epidemiology is implementing the project, with support from the Institute Pasteur NhaTrang, KhanhHoa Department of Health, Monash University,AFAP và the Oxford University Clinical Research Unit. The approach adopted by our research program is highly novel, using a naturally occurring obligate intracellular insect bacterium, Wolbachiapipientis, khổng lồ block transmission of dengue viruses by the primary mosquito vector Aedesaegypti.

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This blocking effect is best described as a vaccine for the mosquito.The Vietnam releases are currently focussed on the field site of Tri Nguyen Island, an island off the coast of NhaTrang, which is situated in KhanhHoa Province on the south central coast of Vietnam. The first release deployed the wMelPop strain of Wolbachia, while the second release is utilizing the wMel strain.The goals of the first two Vietnam pilot releases are:1.Demonstrate both the establishment of Wolbachia infection and invasion into natural mosquito populations.2.Demonstrate that the anti-dengue properties of Wolbachia are present in mosquitoes under field conditions.3.Demonstrate to lớn the community & also other countries that a release is not harmful.The EDPV is beginning the preparation phase for a large-scale Wolbachia release in NhaTrang city. This new project will move lớn a focus on epidemiological outcomes, which will hopefully provide evidence of a reduction in dengue transmission in areas where the Wolbachiamosquitoes occur. It is this new project that the EDPV Project Coordinator will manage.

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